High incidence of epilepsy in children, have a serious impact on health, due to physiological characteristics, combined with neural, humoral aspects of change, so certain aspects differ from adult epilepsy in children.
(1) genetic factors: at present it has been recognized and genetic epilepsy, epilepsy of children and greater impact. The form of epilepsy itself not only with a genetic tendency, and a number of other hereditary diseases, symptoms of epilepsy is often seen, even as the main symptoms, such as phenylketonuria, neurofibromatosis, tuberous sclerosis etc. Clinical evidence for epileptic children with genetic predisposition, when confronted with a morbidity of various General, mild, it can cause seizures. Even without obvious clinical attack or attack demonstrated a threshold lower, EEG spikes or Spike and slow wave discharge occurs.
(2) access to factors: the pathological change in brain of epilepsy, acquired brain damage caused by structural or metabolic lesions of the brain, epilepsy, section of chronic diseases can be static or limitations, or sexual. Brain damage causes a lot of, but more for congenital anomalies in children, birth trauma or injury, brain infection, convulsion, etc.
(3) gender, age at onset and the types of attacks: men more than women in General, to children up to, and the age and the type of attack is closely, such as infantile spasms almost in less than 1 year old, in the pathogenesis of campaign attack at the age of 6, in 1~8sui the pathogenesis of absence seizures, other various types of seizures within the first 10 years of age also. Neonatal seizures are often subtle and is focal seizures, convulsions obvious in older infants and systemic.
(4) episode: incidence of epileptic attack types vary with age, its clinical manifestations of closely related to the maturity of the central nervous system. Subject to common occurs in children of any age outside the Grand Mal, Neonatal seizures the clinical manifestations are mostly stereotyped repetitive actions, and often accompanied by abnormal eye movements.
(5) intellectual change: where there is a clear etiology of brain organic, genetic, metabolic, and abnormal neurological signs, almost all have low intelligence. Younger, higher incidence of mental retardation, and different types of occurrences with mental decline, from high to low, followed by infantile spasms, free attacks, and attack more frequently intelligent lower the higher the rate, serious attack itself can influence intellectual development.
In addition, the onset of epilepsy in children there are in the same patient diversity, induced by variability and adverse factors easily and so on.
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