Pathogenic bacteria and their toxins to enter the human body, can stimulate white blood cells, releasing a substance called neireyuan. It can cause central nervous system synthesis and release of prostaglandins. Prostaglandin and can be made for thermoregulation central nervous system causing fever.
Like believes that fever is a defensive reaction to infection in patients with infection. By fever, can stimulate the body against infection of phagocytosis of mononuclear-macrophage system; formation of pathogen eradication antibodies; enhancement of Leukocyte elimination of pathogens of enzyme activity and detoxification of the liver function. Together, these effects can resist invasion of bacteria on the human body, to promote rehabilitation. High fever but also adverse effects to the human body. High heat body metabolism of nutrients increase, on oxygen consumption also increased when combined with high fever in children in enough of, sometimes diarrhea, digestive disorder, it is prone to metabolic disorders. When heating, child\'s heartbeat is fast, high fever fast when more visible, thereby increasing the burden on the heart. Fever may also result in highly excited in the cerebral cortex, characterized by irritability, there is even a seizure or performance for the high degree of inhibition, Rave, sleeping sickness, and even coma occurs and so on. Fever may also cause excessive consumption of human body, but a defense of infection drop.
Heating for the human body is not necessarily a bad thing, but if you reach the level of high fever, was very prominent downside on human body. Therefore, the application in hyperthermia is only necessary when antipyretic drugs. Antipyretic agents have many kinds of used at present, but the mechanism is essentially the same. Fever itself is caused by the prostaglandin used for thermoregulation hub, and antipyretic agent is by inhibiting prostaglandin synthesis process needs a key-epoxy enzymes, reduce prostaglandin synthesis, so as to achieve aims of antipyretic. Under normal circumstances, epoxy is a normal cell components, on gastric mucosal protection, maintain digestive system function has an important role. Therefore, antipyretic agents are common side effects of digestive system discomfort reactions.
Antipyretic agents reduce prostaglandin production, fundamentally reduce the thermoregulation of Central stimulation. But can reduce body temperature, heat also depends on whether the body can be quickly disseminated into the surrounding environment. Too many children wear as parents easier to heat, is not conducive to dissipation, therefore, after the use of antipyretic drugs are not satisfied with some of hypothermia in children. While parents complaining about bad antipyretic effect, be aware of whether you created a very good thermal conditions for children. Stress again, drugs must be coupled with physical cooling of cooling to achieve good results.
There are caused by pathogenic bacteria of fever is not due, but because of human traumatic tissue destruction and necrosis; vomiting or diarrhea caused by dehydration; summer exposure to hot environments; after head trauma; convulsions or after strenuous exercise, and skin dysplasia caused by thermal barrier and other reasons. Fever is not due to these causes in vivo induced by prostaglandin generates too much, so antipyretic agent cannot meet the satisfaction of the antipyretic effect. These fever in children, use the physical cooling methods only.
No comments:
Post a Comment